In recent years, states have implemented system-wide programs, including the University System of Georgia’s STEM Initiative, to enhance postsecondary science, technology, engineering, and mathematics (STEM) education. This paper presents the results of a review of the scholarly literature and a national Internet survey undertaken to develop a catalogue of state-level STEM enhancement programs, focused on program objectives, demographics, programmatic components, and outcomes. Forty-two states have developed such programs, thirty of which focus specifically on P-16 STEM education.