Peter J. Ludovice's research activities emphasize the use of computer simulation to elucidate the relationship between atomic-level structure and properties of synthetic and biological macromolecules. Insight from computer simulations can more efficiently guide experimental efforts to save millions of dollars on development costs. Particular emphasis is placed on characterizing fundamental ordering and energetic phenomena indicative of superior properties. Ludovice focuses on several areas, including transmembrane proteins, relaxation and gas diffusion in polymer glasses, and polymers for microelectronics applications. He also develops new simulation protocols to model highly viscous systems more efficiently. Additionally, Ludovice is known for his unique approach to classroom instruction, which includes incorporating humor to facilitate learning.